Acne is the most common cutaneous disease affecting teenagers and young adults. It is not physically disabling, and its psychological impact can be striking, according to low confidencedepression, and stress. The psychological effects of embarrassment and fear can impact the social lives and employment of affected individuals. Scars can be disfiguring and lifelong. In one prospective study of 90 patients with acne, they found a significant improvement in self-esteem with acne treatment. Thus, clinicians must be familiar with acne Vulgaris and its treatment.

A terminology change from Propionibacterium acnes to Cutibacterium acnes has been proposed based upon genetic analysis.

Treatments for Acne


Medical therapies for acne target one or more of four key factors that promote the development of acne lesions: follicular hyperproliferation and abnormal desquamation, increased sebum production, Cutibacterium (formerly Propionibacterium) acnes proliferation, and inflammation.

These factors are targeted as follows: 

Follicular hyperproliferation and abnormal desquamation.

  • Topical retinoids  
  • Oral retinoids  
  • Azelaic acid 
  • Salicylic acid 
  • Hormonal therapies

Increased sebum production

  • Oral isotretinoin
  • Hormonal therapies

C. acnes proliferation 

  • Benzoyl peroxide
  • Topical and oral antibiotics
  • Azelaic acid


  • Oral isotretinoin
  • Oral tetracyclines
  • Topical retinoids
  • Azelaic acid


Procedures for Acne

— Chemical Peel

  • Salicylic Acid 
  • Azelaic Acid
  • Yellow Peel 

— Laser Treatment 

— Comedone Extraction

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